Chemoselective debenzylation of N-benzyl tertiary amines with ceric ammonium nitrate

Treatment of a range of N-benzyl tertiary amines with aqueous eerie ammonium nitrate results in N-debenzylation to afford the corresponding secondary amine. Chemoselective mono-W-debenzylation of N-benzyl tertiary amines is shown to occur in the presence of N-benzyl amides, O-benzyl ethers, O-benzyl...

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Bibliographic Details
Main Authors: Bull, S, Davies, S, Fenton, G, Mulvaney, A, Prasad, R, Smith, A
Format: Journal article
Language:English
Published: 2000