Severe cerebral swelling is not observed in children dying with malaria

In an autopsy study in Abidjan, Cote d'lvoire, 14/155 brains of children <13 years had malaria parasites within cerebral blood vessels. This was associated with cerebral swelling (57% of brains), ventricular compression (86%) and mild basal grooving (43%), but not with coning of the medu...

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Main Authors: Lucas, S, Hounnou, A, Bell, J, Peacock, C, Andoh, J, Honde, M, DeCock, K, Warrell, D
Format: Journal article
Language:English
Published: 1996
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author Lucas, S
Hounnou, A
Bell, J
Peacock, C
Andoh, J
Honde, M
DeCock, K
Warrell, D
author_facet Lucas, S
Hounnou, A
Bell, J
Peacock, C
Andoh, J
Honde, M
DeCock, K
Warrell, D
author_sort Lucas, S
collection OXFORD
description In an autopsy study in Abidjan, Cote d'lvoire, 14/155 brains of children <13 years had malaria parasites within cerebral blood vessels. This was associated with cerebral swelling (57% of brains), ventricular compression (86%) and mild basal grooving (43%), but not with coning of the medulla and cerebellum. The pathophysiology of cerebral malaria does not culminate in severe raised intracranial pressure and herniation, and over-concern over the safety of lumbar puncture in malaria may not be warranted.
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spelling oxford-uuid:8c2528ff-12bb-48cb-8955-71fef6a606872022-03-26T22:42:45ZSevere cerebral swelling is not observed in children dying with malariaJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:8c2528ff-12bb-48cb-8955-71fef6a60687EnglishSymplectic Elements at Oxford1996Lucas, SHounnou, ABell, JPeacock, CAndoh, JHonde, MDeCock, KWarrell, DIn an autopsy study in Abidjan, Cote d'lvoire, 14/155 brains of children <13 years had malaria parasites within cerebral blood vessels. This was associated with cerebral swelling (57% of brains), ventricular compression (86%) and mild basal grooving (43%), but not with coning of the medulla and cerebellum. The pathophysiology of cerebral malaria does not culminate in severe raised intracranial pressure and herniation, and over-concern over the safety of lumbar puncture in malaria may not be warranted.
spellingShingle Lucas, S
Hounnou, A
Bell, J
Peacock, C
Andoh, J
Honde, M
DeCock, K
Warrell, D
Severe cerebral swelling is not observed in children dying with malaria
title Severe cerebral swelling is not observed in children dying with malaria
title_full Severe cerebral swelling is not observed in children dying with malaria
title_fullStr Severe cerebral swelling is not observed in children dying with malaria
title_full_unstemmed Severe cerebral swelling is not observed in children dying with malaria
title_short Severe cerebral swelling is not observed in children dying with malaria
title_sort severe cerebral swelling is not observed in children dying with malaria
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AT hounnoua severecerebralswellingisnotobservedinchildrendyingwithmalaria
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AT peacockc severecerebralswellingisnotobservedinchildrendyingwithmalaria
AT andohj severecerebralswellingisnotobservedinchildrendyingwithmalaria
AT hondem severecerebralswellingisnotobservedinchildrendyingwithmalaria
AT decockk severecerebralswellingisnotobservedinchildrendyingwithmalaria
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