Population genomics and transcriptomics of Plasmodium falciparum in Cambodia and Vietnam uncover key components of the artemisinin resistance genetic background
The emergence of Plasmodium falciparum parasites resistant to artemisinins compromises the efficacy of Artemisinin Combination Therapies (ACTs), the global first-line malaria treatment. Artemisinin resistance is a complex genetic trait in which nonsynonymous SNPs in PfK13 cooperate with other geneti...
Հիմնական հեղինակներ: | Nayak, S, Peto, TJ, Kucharski, M, Tripura, R, Callery, JJ, Quang Huy, DT, Gendrot, M, Lek, D, Nghia, HDT, van der Pluijm, RW, Dong, N, Long, LT, Vongpromek, R, Rekol, H, Hoang Chau, N, Miotto, O, Mukaka, M, Dhorda, M, von Seidlein, L, Imwong, M, Roca, X, Day, NPJ, White, NJ, Dondorp, AM |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
Nature Research
2024
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Նմանատիպ նյութեր
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Population genomics and transcriptomics of Plasmodium falciparum in Cambodia and Vietnam uncover key components of the artemisinin resistance genetic background
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Population genomics and transcriptomics of Plasmodium falciparum in Cambodia and Vietnam uncover key components of the artemisinin resistance genetic background
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