Population genomics and transcriptomics of Plasmodium falciparum in Cambodia and Vietnam uncover key components of the artemisinin resistance genetic background
The emergence of Plasmodium falciparum parasites resistant to artemisinins compromises the efficacy of Artemisinin Combination Therapies (ACTs), the global first-line malaria treatment. Artemisinin resistance is a complex genetic trait in which nonsynonymous SNPs in PfK13 cooperate with other geneti...
主要な著者: | , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
フォーマット: | Journal article |
言語: | English |
出版事項: |
Nature Research
2024
|