Adenovirus VA RNAI blocks ASC oligomerization and inhibits NLRP3 inflammasome activation
Virus infected immune cells can rapidly respond to the invader by activating the inflammasome and as a consequence release proinflammatory cytokines and eventually die by pyroptosis. In human adenovirus-5 (Ad5) infected THP-1 cells, inhibition of NLRP3 inflammasome activation was demonstrated by a d...
| Hauptverfasser: | , , , , |
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| Format: | Journal article |
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Frontiers Media
2019
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