Kinetics of core histones in living human cells: little exchange of H3 and H4 and some rapid exchange of H2B

Histones H2A and H2B form part of the same nucleosomal structure as H3 and H4. Stable HeLa cell lines expressing histones H2B, H3, and H4 tagged with green fluorescent protein (GFP) were established; the tagged molecules were assembled into nucleosomes. Although H2B-GFP was distributed like DNA, H3-...

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Bibliographic Details
Main Authors: Kimura, H, Cook, P
Format: Journal article
Language:English
Published: Rockefeller University Press 2001
Subjects: