The role of p97 cofactors SPRTN and FAF1 in DNA replication
<p>It is well known that cancer cells are loaded with excess proteins. To survive this proteotoxic crisis cancer cells rely heavily on the ubiquitin proteasome system (UPS). Valosin containing protein (VCP) or p97 has recently emerged as a central player of UPS. Moreover, p97 inhibitors wer...
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| Μορφή: | Thesis |
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2016
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