Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression.

Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression.

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Although genome-wide association studies (GWAS) have identified the existence of numerous population-based cancer susceptibility loci, mechanistic insights remain limited, particularly for intergenic polymorphisms. Here, we show that polymorphism at a remote intergenic region on chromosome 11q13.3,...

Bibliografske podrobnosti
Main Authors:	Schödel, J, Bardella, C, Sciesielski, L, Brown, J, Pugh, C, Buckle, V, Tomlinson, I, Ratcliffe, P, Mole, DR
Format:	Journal article
Jezik:	English
Izdano:	2012

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