Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.

BACKGROUND: The strong observational association between total homocysteine (tHcy) concentrations and risk of coronary artery disease (CAD) and the null associations in the homocysteine-lowering trials have prompted the need to identify genetic variants associated with homocysteine concentrations an...

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Hlavní autoři: van Meurs, J, Pare, G, Schwartz, S, Hazra, A, Tanaka, T, Vermeulen, S, Cotlarciuc, I, Yuan, X, Mälarstig, A, Bandinelli, S, Bis, J, Blom, H, Brown, M, Chen, C, Chen, Y, Clarke, R, Dehghan, A, Erdmann, J, Ferrucci, L, Hamsten, A, Hofman, A, Hunter, D, Goel, A, Johnson, A, Kathiresan, S
Médium: Journal article
Jazyk:English
Vydáno: 2013