Thioguanine-related veno-occlusive disease (VOD) of the liver in children with acute lymphoblastic leukaemia (ALL): Report from United Kingdom Medical Research Council (UK MRC) trial ALL97.

Bibliographic Details
Main Authors:	Vora, A, Mitchell, C, Kinsey, S, Richards, S, Eden, T, Lilleyman, J, Lennard, L
Format:	Conference item
Published:	2002

Thioguanine compared with mercaptopurine in childhood lymphoblastic leukaemia: Results of the United Kingdom medical research council randomised trial ALL97.
by: Lennard, L, et al.
Published: (2005)

Variables affecting kinetics of minimal residual disease clearance in children with lymphoblastic leukaemia; Results of the United Kingdom Medical Research Council (UK MRC) protocols ALL97, ALL97/99 and ALL2003.
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The clinical pharmacology of thioguanine vs. mercaptopurine in ALL97, a randomized trial for the treatment of childhood lymphoblastic leukaemia
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Benefit of intensified treatment for all children with acute lymphoblastic leukaemia: results from MRC UKALL XI and MRC ALL97 randomised trials. UK Medical Research Council's Working Party on Childhood Leukaemia.
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Benefit of targeted intensification for NCI high risk childhood lymphoblastic leukaemia: Results of the United Kingdom medical research council trial ALL97 and ALL97/99.
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MRC ALL97/99 - A randomized comparison of dexamethasone versus prednisolone and thioguanine versus mercaptopurine in the treatment of childhood acute lymphoblastic leukemia.
by: Mitchell, C, et al.
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Benefit of dexamethasone compared with prednisolone for childhood acute lymphoblastic leukaemia: results of the UK Medical Research Council ALL97 randomized trial.
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Karyotype and prognosis in childhood acute lymphoblastic leukemia (ALL) in the UK medical research council (MRC) ALL97 trial.
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Toxicity and efficacy of 6-thioguanine versus 6-mercaptopurine in childhood lymphoblastic leukaemia: a randomised trial.
by: Vora, A, et al.
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Thioguanine versus mercaptopurine in ALL97: thiopurine metabolism and treatment outcome
by: Lennard, L, et al.
Published: (2008)

The impact of risk stratification by early bone-marrow response in childhood lymphoblastic leukaemia: results from the United Kingdom Medical Research Council trial ALL97 and ALL97/99.
by: Mitchell, C, et al.
Published: (2009)

Prognostic Relevance of Cytogenetics in Childhood Acute Lymphoblastic Leukaemia (ALL): Final Results From MRC ALL97.
by: Moor-Man, A, et al.
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The thiopurine methyltransferase genetic polymorphism is associated with thioguanine-related veno-occlusive disease of the liver in children with acute lymphoblastic leukemia.
by: Lennard, L, et al.
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The thiopurine methyltransferase TPMT *1/*3A genotype is associated with a better treatment outcome in the UK ALL97 trial for childhood acute lymphoblastic leukaemia; TPMT heterozygosity is not associated with secondary cancers
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Acute lymphoblastic leukaemia has a poor outcome in children with Down syndrome due to infective death in remission - (Results of UK MRC ALL 97 trial).
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Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial.
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Demographic, clinical, and outcome features of children with acute lymphoblastic leukemia and CRLF2 deregulation: results from the MRC ALL97 clinical trial.
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Efficacy and Toxicity of Pegylated Asparaginase in the Treatment of Children and Young Adults with Acute Lymphoblastic Leukaemia: Results of the United Kingdom Medical Research Council (MRC) Trial UKALL 2003
by: Vora, A, et al.
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TEL-AML1 fusion in childhood acute lymphoblastic leukaemia (ALL): Demographics, clinical features, cytogenetic characteristics and prognosis
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Long-term follow-up of the United Kingdom Medical Research Council protocols for childhood acute lymphoblastic leukaemia, 1980-1997
by: Eden, O, et al.
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Adolescents with acute lymphoblastic leukaemia: outcome on UK national paediatric (ALL97) and adult (UKALLXII/E2993) trials.
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Three distinct subgroups of hypodiploidy in acute lymphoblastic leukemia in UK MRC trials.
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Thioguanine used in maintenance therapy of chronic myeloid leukaemia causes non-cirrhotic portal hypertension. Results from MRC CML. II. Trial comparing busulphan with busulphan and thioguanine.
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A third intensive block of treatment at 35 weeks improves outcome in childhood ALL: Preliminary results from the UKALLXI and ALL97 randomised trials.
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by: Harrison, G, et al.
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by: Sive, J, et al.
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Thioguanine-related veno-occlusive disease (VOD) of the liver in children with acute lymphoblastic leukaemia (ALL): Report from United Kingdom Medical Research Council (UK MRC) trial ALL97.

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