Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes.
Mosquitoes are vectors of parasitic and viral diseases of immense importance for public health. The acquisition of the genome sequence of the yellow fever and Dengue vector, Aedes aegypti (Aa), has enabled a comparative phylogenomic analysis of the insect immune repertoire: in Aa, the malaria vector...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2007
|
| _version_ | 1826284235947769856 |
|---|---|
| author | Waterhouse, R Kriventseva, E Meister, S Xi, Z Alvarez, K Bartholomay, L Barillas-Mury, C Bian, G Blandin, S Christensen, B Dong, Y Jiang, H Kanost, MR Koutsos, A Levashina, E Li, J Ligoxygakis, P Maccallum, R Mayhew, G Mendes, A Michel, K Osta, M Paskewitz, S Shin, S Vlachou, D |
| author_facet | Waterhouse, R Kriventseva, E Meister, S Xi, Z Alvarez, K Bartholomay, L Barillas-Mury, C Bian, G Blandin, S Christensen, B Dong, Y Jiang, H Kanost, MR Koutsos, A Levashina, E Li, J Ligoxygakis, P Maccallum, R Mayhew, G Mendes, A Michel, K Osta, M Paskewitz, S Shin, S Vlachou, D |
| author_sort | Waterhouse, R |
| collection | OXFORD |
| description | Mosquitoes are vectors of parasitic and viral diseases of immense importance for public health. The acquisition of the genome sequence of the yellow fever and Dengue vector, Aedes aegypti (Aa), has enabled a comparative phylogenomic analysis of the insect immune repertoire: in Aa, the malaria vector Anopheles gambiae (Ag), and the fruit fly Drosophila melanogaster (Dm). Analysis of immune signaling pathways and response modules reveals both conservative and rapidly evolving features associated with different functional gene categories and particular aspects of immune reactions. These dynamics reflect in part continuous readjustment between accommodation and rejection of pathogens and suggest how innate immunity may have evolved. |
| first_indexed | 2024-03-07T01:10:50Z |
| format | Journal article |
| id | oxford-uuid:8cf3151f-b321-40f8-bccc-992711b53ac1 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T01:10:50Z |
| publishDate | 2007 |
| record_format | dspace |
| spelling | oxford-uuid:8cf3151f-b321-40f8-bccc-992711b53ac12022-03-26T22:48:12ZEvolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:8cf3151f-b321-40f8-bccc-992711b53ac1EnglishSymplectic Elements at Oxford2007Waterhouse, RKriventseva, EMeister, SXi, ZAlvarez, KBartholomay, LBarillas-Mury, CBian, GBlandin, SChristensen, BDong, YJiang, HKanost, MRKoutsos, ALevashina, ELi, JLigoxygakis, PMaccallum, RMayhew, GMendes, AMichel, KOsta, MPaskewitz, SShin, SVlachou, DMosquitoes are vectors of parasitic and viral diseases of immense importance for public health. The acquisition of the genome sequence of the yellow fever and Dengue vector, Aedes aegypti (Aa), has enabled a comparative phylogenomic analysis of the insect immune repertoire: in Aa, the malaria vector Anopheles gambiae (Ag), and the fruit fly Drosophila melanogaster (Dm). Analysis of immune signaling pathways and response modules reveals both conservative and rapidly evolving features associated with different functional gene categories and particular aspects of immune reactions. These dynamics reflect in part continuous readjustment between accommodation and rejection of pathogens and suggest how innate immunity may have evolved. |
| spellingShingle | Waterhouse, R Kriventseva, E Meister, S Xi, Z Alvarez, K Bartholomay, L Barillas-Mury, C Bian, G Blandin, S Christensen, B Dong, Y Jiang, H Kanost, MR Koutsos, A Levashina, E Li, J Ligoxygakis, P Maccallum, R Mayhew, G Mendes, A Michel, K Osta, M Paskewitz, S Shin, S Vlachou, D Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes. |
| title | Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes. |
| title_full | Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes. |
| title_fullStr | Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes. |
| title_full_unstemmed | Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes. |
| title_short | Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes. |
| title_sort | evolutionary dynamics of immune related genes and pathways in disease vector mosquitoes |
| work_keys_str_mv | AT waterhouser evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT kriventsevae evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT meisters evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT xiz evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT alvarezk evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT bartholomayl evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT barillasmuryc evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT biang evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT blandins evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT christensenb evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT dongy evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT jiangh evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT kanostmr evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT koutsosa evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT levashinae evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT lij evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT ligoxygakisp evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT maccallumr evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT mayhewg evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT mendesa evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT michelk evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT ostam evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT paskewitzs evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT shins evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes AT vlachoud evolutionarydynamicsofimmunerelatedgenesandpathwaysindiseasevectormosquitoes |