Structure–function relationships of human JmjC oxygenases — demethylases versus hydroxylases

The Jumonji-C (JmjC) subfamily of 2-oxoglutarate (2OG)-dependent oxygenases are of biomedical interest because of their roles in the regulation of gene expression and protein biosynthesis. Human JmjC 2OG oxygenases catalyze oxidative modifications to give either chemically stable alcohol products, o...

Full description

Bibliographic Details
Main Authors: Markolovic, S, Leissing, T, Chowdhury, R, Wilkins, S, Lu, X, Schofield, C
Format: Journal article
Language:English
Published: Elsevier 2016