Structure–function relationships of human JmjC oxygenases — demethylases versus hydroxylases
The Jumonji-C (JmjC) subfamily of 2-oxoglutarate (2OG)-dependent oxygenases are of biomedical interest because of their roles in the regulation of gene expression and protein biosynthesis. Human JmjC 2OG oxygenases catalyze oxidative modifications to give either chemically stable alcohol products, o...
Main Authors: | , , , , , |
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Format: | Journal article |
Sprog: | English |
Udgivet: |
Elsevier
2016
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