Treatment for unicameral bone cysts in long bones: an evidence based review
<p style="text-align:justify;">The purpose of this paper is to perform an evidence based review for treatment of unicameral bone cysts. A search of MEDLINE (1966 to 2009) was conducted and the studies were classified according to levels of evidence. This review includes only compara...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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PAGEpress
2010
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| _version_ | 1797081186315534336 |
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| author | Donaldson, S Chundamala, J Yandow, S Wright, J |
| author_facet | Donaldson, S Chundamala, J Yandow, S Wright, J |
| author_sort | Donaldson, S |
| collection | OXFORD |
| description | <p style="text-align:justify;">The purpose of this paper is to perform an evidence based review for treatment of unicameral bone cysts. A search of MEDLINE (1966 to 2009) was conducted and the studies were classified according to levels of evidence. This review includes only comparative Level I-III studies. The systematic review identified 16 studies. There is one level I study, one level II study and the remaining 14 studies are level III. Seven of the sixteen studies had statistically different results: three studies indicated that steroid injection was superior to bone marrow injection or curettage and bone grafting; one study indicated that cannulated screws were superior to steroid injections; one study indicated resection and myoplasty was superior to steroid injection; one study indicated a combination of steroid, demineralized bone matrix and bone marrow aspirate, and curettage and bone grafting were superior to steroid injection; and one study indicated that curettage and bone grafting was superior to non-operative immobilization. Based on one Level I study, including a limited number of individuals, steroid injection seems to be superior to bone marrow injection. As steroid injections have already demonstrated superiority over bone marrow injections in a randomized clinical trial, the next step would be a prospective trial comparing steroid injections with other treatments.</p> |
| first_indexed | 2024-03-07T01:11:00Z |
| format | Journal article |
| id | oxford-uuid:8d014192-9d22-48e6-9741-84dfb3b3cf94 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T01:11:00Z |
| publishDate | 2010 |
| publisher | PAGEpress |
| record_format | dspace |
| spelling | oxford-uuid:8d014192-9d22-48e6-9741-84dfb3b3cf942022-03-26T22:48:25ZTreatment for unicameral bone cysts in long bones: an evidence based reviewJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:8d014192-9d22-48e6-9741-84dfb3b3cf94EnglishSymplectic Elements at OxfordPAGEpress2010Donaldson, SChundamala, JYandow, SWright, J <p style="text-align:justify;">The purpose of this paper is to perform an evidence based review for treatment of unicameral bone cysts. A search of MEDLINE (1966 to 2009) was conducted and the studies were classified according to levels of evidence. This review includes only comparative Level I-III studies. The systematic review identified 16 studies. There is one level I study, one level II study and the remaining 14 studies are level III. Seven of the sixteen studies had statistically different results: three studies indicated that steroid injection was superior to bone marrow injection or curettage and bone grafting; one study indicated that cannulated screws were superior to steroid injections; one study indicated resection and myoplasty was superior to steroid injection; one study indicated a combination of steroid, demineralized bone matrix and bone marrow aspirate, and curettage and bone grafting were superior to steroid injection; and one study indicated that curettage and bone grafting was superior to non-operative immobilization. Based on one Level I study, including a limited number of individuals, steroid injection seems to be superior to bone marrow injection. As steroid injections have already demonstrated superiority over bone marrow injections in a randomized clinical trial, the next step would be a prospective trial comparing steroid injections with other treatments.</p> |
| spellingShingle | Donaldson, S Chundamala, J Yandow, S Wright, J Treatment for unicameral bone cysts in long bones: an evidence based review |
| title | Treatment for unicameral bone cysts in long bones: an evidence based review |
| title_full | Treatment for unicameral bone cysts in long bones: an evidence based review |
| title_fullStr | Treatment for unicameral bone cysts in long bones: an evidence based review |
| title_full_unstemmed | Treatment for unicameral bone cysts in long bones: an evidence based review |
| title_short | Treatment for unicameral bone cysts in long bones: an evidence based review |
| title_sort | treatment for unicameral bone cysts in long bones an evidence based review |
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