Prediction of cccDNA dynamics in hepatitis B patients by a combination of serum surrogate markers

Quantification of intrahepatic covalently closed circular DNA (cccDNA) is a key for evaluating an elimination of hepatitis B virus (HBV) in infected patients. However, quantifying cccDNA requires invasive methods such as a liver biopsy, which makes it impractical to access the dynamics of cccDNA in...

Full description

Bibliographic Details
Main Authors: Kim, KS, Iwamoto, M, Kitagawa, K, Park, H, Hayashi, S, Tsukuda, S, Matsui, T, Atsukawa, M, Matsuura, K, Chuaypen, N, Tangkijvanich, P, Allweiss, L, Nishiyama, T, Nakamura, N, Fujita, Y, Kawakami, E, Nakaoka, S, Muramatsu, M, Aihara, K, Wakita, T, Perelson, AS, Dandri, M, Watashi, K, Iwami, S
Format: Journal article
Language:English
Published: Public Library of Science 2025