Influence of plasma glutathione levels on radiation mucositis.

Influence of plasma glutathione levels on radiation mucositis.

PURPOSE: To test the hypothesis that there is a link between plasma glutathione (GSH) or other antioxidants (uric acid, ascorbate) and the severity of radiation mucositis following radiation treatment of tumors of the head and neck. PATIENTS AND METHODS: Patients with carcinomas of the head-and-neck...

Full description

Bibliographic Details
Main Authors:	Wardman, P, Folkes, L, Bentzen, S, Stratford, MR, Hoskin, P, Phillips, H, Jackson, S
Format:	Journal article
Language:	English
Published:	2001

Similar Items

Kinetics of the reaction between nitric oxide and glutathione: implications for thiol depletion in cells.
by: Folkes, L, et al.
Published: (2004)

Kinetics of reduction of tyrosine phenoxyl radicals by glutathione.
by: Folkes, L, et al.
Published: (2011)

Revisiting the interaction of the radical anion metabolite of nitrofurantoin with glutathione.
by: Miller, C, et al.
Published: (2002)

Oxidative metabolism of combretastatin A-1 produces quinone intermediates with the potential to bind to nucleophiles and to enhance oxidative stress via free radicals.
by: Folkes, L, et al.
Published: (2007)

5-Fluoroindole-3-acetic acid: a prodrug activated by a peroxidase with potential for use in targeted cancer therapy.
by: Folkes, L, et al.
Published: (2002)

A validated HPLC method with fluorescence detection for the glucuronides of Combretastatin A1 in human plasma, and studies on their cis-trans isomerisation.
by: Stratford, MR, et al.
Published: (2012)

Validation of a method for the determination of the anticancer agent Combretastatin A1 phosphate (CA1P, OXi4503) in human plasma by HPLC with post-column photolysis and fluorescence detection.
by: Stratford, MR, et al.
Published: (2011)

Effect of local radiotherapy for bone pain on urinary markers of osteoclast activity.
by: Hoskin, P, et al.
Published: (2000)

Quantitative determination of the anticancer prodrug combretastatin A1 phosphate (OXi4503, CA1P), the active CA1 and its glucuronide metabolites in human urine and of CA1 in plasma by HPLC with mass spectrometric detection.
by: Stratford, MR, et al.
Published: (2012)

Radiosensitization by nitric oxide at low radiation doses.
by: Wardman, P, et al.
Published: (2007)

Oxidative activation of indole-3-acetic acids to cytotoxic species- a potential new role for plant auxins in cancer therapy.
by: Folkes, L, et al.
Published: (2001)

Enhancing the efficacy of photodynamic cancer therapy by radicals from plant auxin (indole-3-acetic acid).
by: Folkes, L, et al.
Published: (2003)

A validated HPLC method with fluorescence detection for the glucuronides of Combretastatin A1 in human plasma, and studies on their cis-trans isomerisation
by: Stratford, M, et al.
Published: (2012)

Influence of occupational exposure to low-dose ionizing radiation on the plasma activity of superoxide dismutase and glutathione level
by: Đurović Branka, et al.
Published: (2008-01-01)

Validation of a method for the determination of the anticancer agent Combretastatin A1 phosphate (CA1P, OXi4503) in human plasma by HPLC with post-column photolysis and fluorescence detection
by: Stratford, M, et al.
Published: (2011)

Measurement of plasma 5-hydroxyindoleacetic acid as a possible clinical surrogate marker for the action of antivascular agents.
by: Kestell, P, et al.
Published: (2001)

Reactivity toward thiols and cytotoxicity of 3-methylene-2-oxindoles, cytotoxins from indole-3-acetic acids, on activation by peroxidases.
by: Folkes, L, et al.
Published: (2002)

Halogenated indole-3-acetic acids as oxidatively activated prodrugs with potential for targeted cancer therapy.
by: Rossiter, S, et al.
Published: (2002)

Effect of nitric-oxide synthesis on tumour blood volume and vascular activity: a phase I study.
by: Ng, Q, et al.
Published: (2007)

Plasma glutathione and oxidized glutathione level, glutathione/oxidized glutathione ratio, and albumin concentration in complicated and uncomplicated falciparum malaria
by: Loeki Enggar Fitri, et al.
Published: (2016-08-01)

Oxidation of tetrahydrobiopterin by biological radicals and scavenging of the trihydrobiopterin radical by ascorbate.
by: Patel, K, et al.
Published: (2002)

Radiation chemistry comes before radiation biology.
by: O'Neill, P, et al.
Published: (2009)

Kinetics of reaction of nitrogen dioxide with dihydrorhodamine and the reaction of the dihydrorhodamine radical with oxygen: implications for quantifying peroxynitrite formation in cells.
by: Folkes, L, et al.
Published: (2009)

Comparison of plasma malondialdehyde, glutathione, glutathione peroxidase, hydroxyproline and selenium levels in patients with vitiligo and healthy controls
by: Ozturk I, et al.
Published: (2008-01-01)

Thiyl radicals react with nitric oxide to form S-nitrosothiols with rate constants near the diffusion-controlled limit.
by: Madej, E, et al.
Published: (2008)

Is sensitization with nicotinamide and carbogen dependent on nicotinamide concentration at the time of irradiation?
by: Rojas, A, et al.
Published: (2004)

Effect of atrazine on glutathione levels, glutathione s-transferase and glutathione reductase activities in pea and wheat plants
by: Lyuba P.-E. Miteva, et al.
Published: (2004-03-01)

Development of a novel enzyme/prodrug combination for gene therapy of cancer: horseradish peroxidase/indole-3-acetic acid.
by: Greco, O, et al.
Published: (2000)

Plasma levels of CD36 and glutathione as biomarkers for ruptured intracranial aneurysm
by: Wang Hanbin, et al.
Published: (2023-12-01)

Relating mood to plasma glutathione and BDNF levels in patients with bipolar disorder
by: Singh, N, et al.
Published: (2013)

Blood Plasma Quality Control by Plasma Glutathione Status
by: Tamara Tomin, et al.
Published: (2021-05-01)

Modification of DNA damage mechanisms by nitric oxide during ionizing radiation.
by: Folkes, L, et al.
Published: (2013)

Radiation-Induced Oral Mucositis
by: Osama Muhammad Maria, et al.
Published: (2017-05-01)

DNA damage induced by nitric oxide during ionizing radiation is enhanced at replication
by: Folkes, L, et al.
Published: (2013)

DNA damage induced by nitric oxide during ionizing radiation is enhanced at replication.
by: Folkes, L, et al.
Published: (2013)

Effects of Occupational Inorganic Dust Exposure on Plasma Glutathione
by: Pavlina L. Gidikova, et al.
Published: (2021-07-01)

The changing role of radiation therapy in the management of oligometastatic disease
by: H. Tharmalingham, et al.
Published: (2017-03-01)

Oral administration of cystine and theanine attenuates 5-fluorouracil-induced intestinal mucositis and diarrhea by suppressing both glutathione level decrease and ROS production in the small intestine of mucositis mouse model
by: Junya Yoneda, et al.
Published: (2021-12-01)

Hypoxia-driven elimination of thiopurines from their nitrobenzyl prodrugs.
by: Thomson, P, et al.
Published: (2007)

The influence of hydroquinone on tyrosinase kinetics.
by: Stratford, MR, et al.
Published: (2012)