HMOX1 gene promoter alleles and high HO-1 levels are associated with severe malaria in Gambian children.

HMOX1 gene promoter alleles and high HO-1 levels are associated with severe malaria in Gambian children.

Heme oxygenase 1 (HO-1) is an essential enzyme induced by heme and multiple stimuli associated with critical illness. In humans, polymorphisms in the HMOX1 gene promoter may influence the magnitude of HO-1 expression. In many diseases including murine malaria, HO-1 induction produces protective anti...

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Bibliographic Details
Main Authors:	Walther, M, De Caul, A, Aka, P, Njie, M, Amambua-Ngwa, A, Walther, B, Predazzi, I, Cunnington, A, Deininger, S, Takem, E, Ebonyi, A, Weis, S, Walton, R, Rowland-Jones, S, Sirugo, G, Williams, S, Conway, D
Format:	Journal article
Language:	English
Published:	Public Library of Science 2012

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