Impact of a newly constructed motor vehicle road on altitude illness in the Nepal Himalayas.

<h4>Objective</h4> <p>This study investigates the impact of motor vehicle travel along a newly constructed road from Besisahar (760 m) to Manang ( 3540 m) in Nepal on altitude sickness (including acute mountain sickness (AMS), high altitude cerebral edema (HACE) and high altitude...

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Main Authors: Reisman, J, Deonarain, D, Basnyat, B
Format: Journal article
Language:English
Published: Elsevier 2017
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author Reisman, J
Deonarain, D
Basnyat, B
author_facet Reisman, J
Deonarain, D
Basnyat, B
author_sort Reisman, J
collection OXFORD
description <h4>Objective</h4> <p>This study investigates the impact of motor vehicle travel along a newly constructed road from Besisahar (760 m) to Manang ( 3540 m) in Nepal on altitude sickness (including acute mountain sickness (AMS), high altitude cerebral edema (HACE) and high altitude pulmonary edema (HAPE)). </p> <h4>Methods</h4> <p>We enrolled all patients diagnosed with altitude sickness in the Himalayan Rescue Association (HRA) Manang clinic in fall 2016. Phi coefficients were calculated to test for an association between Nepali ethnicity and rapid ascent by motor vehicle. A retrospective chart review looked at all altitude sickness patients from 2010 to 2016. </p> <h4>Results</h4> <p>In fall 2016, more than half (53.8%) of altitude sickness patients traveled to Manang by motor vehicle, and one-third (33%) reached Manang from low altitude Besisahar in 2 or fewer days. Nepali ethnicity had a significant association with motor vehicle travel (phi +0.69, p&lt;0.0001), as well as with rapid ascent to Manang (phi +0.72, p&lt;0.0001). Compared to previous seasons, fall 2016 saw the highest number of patients with altitude sickness, as well as the highest number of patients traveling to Manang by vehicle and reaching Manang in 2 or fewer days, all showing a significant increase comprared to season prior to the road’s completion (p=0.0001, p&lt;0.0001 and p&lt;0.0001, respectively).</p> <h4>Conclusions</h4> <p>Rapid ascent by the newly- constructed road from Besisahar to Manang appears to be related to a significant increase in the number of patients with all forms of altitude sickness, especially among Nepalis. An educational intervention is urgently needed.</p>
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spelling oxford-uuid:8d63f739-2672-40ce-81cd-4a9c4d39eeef2022-03-26T22:50:57ZImpact of a newly constructed motor vehicle road on altitude illness in the Nepal Himalayas.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:8d63f739-2672-40ce-81cd-4a9c4d39eeefEnglishSymplectic Elements at OxfordElsevier2017Reisman, JDeonarain, DBasnyat, B <h4>Objective</h4> <p>This study investigates the impact of motor vehicle travel along a newly constructed road from Besisahar (760 m) to Manang ( 3540 m) in Nepal on altitude sickness (including acute mountain sickness (AMS), high altitude cerebral edema (HACE) and high altitude pulmonary edema (HAPE)). </p> <h4>Methods</h4> <p>We enrolled all patients diagnosed with altitude sickness in the Himalayan Rescue Association (HRA) Manang clinic in fall 2016. Phi coefficients were calculated to test for an association between Nepali ethnicity and rapid ascent by motor vehicle. A retrospective chart review looked at all altitude sickness patients from 2010 to 2016. </p> <h4>Results</h4> <p>In fall 2016, more than half (53.8%) of altitude sickness patients traveled to Manang by motor vehicle, and one-third (33%) reached Manang from low altitude Besisahar in 2 or fewer days. Nepali ethnicity had a significant association with motor vehicle travel (phi +0.69, p&lt;0.0001), as well as with rapid ascent to Manang (phi +0.72, p&lt;0.0001). Compared to previous seasons, fall 2016 saw the highest number of patients with altitude sickness, as well as the highest number of patients traveling to Manang by vehicle and reaching Manang in 2 or fewer days, all showing a significant increase comprared to season prior to the road’s completion (p=0.0001, p&lt;0.0001 and p&lt;0.0001, respectively).</p> <h4>Conclusions</h4> <p>Rapid ascent by the newly- constructed road from Besisahar to Manang appears to be related to a significant increase in the number of patients with all forms of altitude sickness, especially among Nepalis. An educational intervention is urgently needed.</p>
spellingShingle Reisman, J
Deonarain, D
Basnyat, B
Impact of a newly constructed motor vehicle road on altitude illness in the Nepal Himalayas.
title Impact of a newly constructed motor vehicle road on altitude illness in the Nepal Himalayas.
title_full Impact of a newly constructed motor vehicle road on altitude illness in the Nepal Himalayas.
title_fullStr Impact of a newly constructed motor vehicle road on altitude illness in the Nepal Himalayas.
title_full_unstemmed Impact of a newly constructed motor vehicle road on altitude illness in the Nepal Himalayas.
title_short Impact of a newly constructed motor vehicle road on altitude illness in the Nepal Himalayas.
title_sort impact of a newly constructed motor vehicle road on altitude illness in the nepal himalayas
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