Step 4: stick or twist? A review of step 4 asthma therapy
Many people with asthma do not achieve disease control, despite bronchodilators and inhaled corticosteroid therapy. People with uncontrolled asthma are at higher risk of an asthma attack and death, with mortality rates estimated at 1000 deaths/year in England and Wales. The recent National Review of...
| Main Authors: | , , |
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| Format: | Journal article |
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BMJ Publishing Group
2016
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| _version_ | 1797081267989118976 |
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| author | Slater, M Pavord, I Shaw, D |
| author_facet | Slater, M Pavord, I Shaw, D |
| author_sort | Slater, M |
| collection | OXFORD |
| description | Many people with asthma do not achieve disease control, despite bronchodilators and inhaled corticosteroid therapy. People with uncontrolled asthma are at higher risk of an asthma attack and death, with mortality rates estimated at 1000 deaths/year in England and Wales. The recent National Review of Asthma Deaths (NRAD) report, ‘Why asthma still kills’, recommended that patients at step 4 or 5 of the British Thoracic Society/Scottish Intercollegiate Guidelines Network (BTS/SIGN) guidance must be referred to a specialist asthma service. This article reviews the 2014 evidence base for therapy of asthma patients at BTS/SIGN step 4 of the treatment cascade, in response to key findings of the NRAD report and lack of preferred treatment option at this step. |
| first_indexed | 2024-03-07T01:12:12Z |
| format | Journal article |
| id | oxford-uuid:8d6700b9-e075-4d57-ad00-7806f6e774b5 |
| institution | University of Oxford |
| last_indexed | 2024-03-07T01:12:12Z |
| publishDate | 2016 |
| publisher | BMJ Publishing Group |
| record_format | dspace |
| spelling | oxford-uuid:8d6700b9-e075-4d57-ad00-7806f6e774b52022-03-26T22:51:03ZStep 4: stick or twist? A review of step 4 asthma therapyJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:8d6700b9-e075-4d57-ad00-7806f6e774b5Symplectic Elements at OxfordBMJ Publishing Group2016Slater, MPavord, IShaw, DMany people with asthma do not achieve disease control, despite bronchodilators and inhaled corticosteroid therapy. People with uncontrolled asthma are at higher risk of an asthma attack and death, with mortality rates estimated at 1000 deaths/year in England and Wales. The recent National Review of Asthma Deaths (NRAD) report, ‘Why asthma still kills’, recommended that patients at step 4 or 5 of the British Thoracic Society/Scottish Intercollegiate Guidelines Network (BTS/SIGN) guidance must be referred to a specialist asthma service. This article reviews the 2014 evidence base for therapy of asthma patients at BTS/SIGN step 4 of the treatment cascade, in response to key findings of the NRAD report and lack of preferred treatment option at this step. |
| spellingShingle | Slater, M Pavord, I Shaw, D Step 4: stick or twist? A review of step 4 asthma therapy |
| title | Step 4: stick or twist? A review of step 4 asthma therapy |
| title_full | Step 4: stick or twist? A review of step 4 asthma therapy |
| title_fullStr | Step 4: stick or twist? A review of step 4 asthma therapy |
| title_full_unstemmed | Step 4: stick or twist? A review of step 4 asthma therapy |
| title_short | Step 4: stick or twist? A review of step 4 asthma therapy |
| title_sort | step 4 stick or twist a review of step 4 asthma therapy |
| work_keys_str_mv | AT slaterm step4stickortwistareviewofstep4asthmatherapy AT pavordi step4stickortwistareviewofstep4asthmatherapy AT shawd step4stickortwistareviewofstep4asthmatherapy |