Targeting interstrand crosslink repair to improve chemotherapeutic strategies
<p>Many clinically effective chemotherapeutic agents exert their toxicity through formation of DNA interstrand cross-links (ICL). These prevent the replication and transcription of DNA and if unrepaired lead to cell death.</p> <p>Despite the success of ICL inducing agents in treati...
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| Format: | Thesis |
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2017
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