Targeting interstrand crosslink repair to improve chemotherapeutic strategies

<p>Many clinically effective chemotherapeutic agents exert their toxicity through formation of DNA interstrand cross-links (ICL). These prevent the replication and transcription of DNA and if unrepaired lead to cell death.</p> <p>Despite the success of ICL inducing agents in treati...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолч: Castle, L
Бусад зохиолчид: McHugh, P
Формат: Дипломын ажил
Хэвлэсэн: 2017