Facilitation by intracellular carbonic anhydrase of Na+–HCO3− co‐transport but not Na+/H+ exchange activity in the mammalian ventricular myocyte

Facilitation by intracellular carbonic anhydrase of Na+–HCO3− co‐transport but not Na+/H+ exchange activity in the mammalian ventricular myocyte

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Carbonic anhydrase enzymes (CAs) catalyse the reversible hydration of CO2 to H+ and HCO3− ions. This catalysis is proposed to be harnessed by acid/base transporters, to facilitate their transmembrane flux activity, either through direct protein–protein binding (a ‘transport metabolon’) or local func...

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Dettagli Bibliografici
Autori principali:	Villafuerte, F, Swietach, P, Youm, J, Ford, K, Cardenas, R, Supuran, C, Cobden, P, Rohling, M, Vaughan-Jones, R
Natura:	Journal article
Lingua:	English
Pubblicazione:	Wiley 2013

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