High resolution IgH repertoire analysis reveals fetal liver as the likely origin of life-long, innate B lymphopoiesis in humans

High resolution IgH repertoire analysis reveals fetal liver as the likely origin of life-long, innate B lymphopoiesis in humans

The ontogeny of the natural, public IgM repertoire remains incompletely explored. Here, high-resolution immunogenetic analysis of B cells from (unrelated) fetal, child, and adult samples, shows that although fetal liver (FL) and bone marrow (FBM) IgM repertoires are equally diversified, FL is the ma...

Podrobná bibliografie
Hlavní autoři:	Roy, A, Bystry, V, Bohn, G, Goudevenou, K, Reigl, T, Papaioannou, M, Krejci, A, O'Byrne, S, Chaidos, A, Grioni, A, Darzentas, N, Roberts, I, Karadimitris, A
Médium:	Journal article
Jazyk:	English
Vydáno:	Elsevier 2017

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