Model suggesting that replication of influenza virus is regulated by stabilization of replicative intermediates.
The RNA-dependent RNA polymerase of influenza A virus is responsible for both transcription and replication of negative-sense viral RNA. It is thought that a "switching" mechanism regulates the transition between these activities. We demonstrate that, in the presence of preexisting viral R...
Main Authors: | Vreede, F, Jung, T, Brownlee, G |
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Format: | Journal article |
Language: | English |
Published: |
2004
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