Model suggesting that replication of influenza virus is regulated by stabilization of replicative intermediates.

The RNA-dependent RNA polymerase of influenza A virus is responsible for both transcription and replication of negative-sense viral RNA. It is thought that a "switching" mechanism regulates the transition between these activities. We demonstrate that, in the presence of preexisting viral R...

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Detalhes bibliográficos
Main Authors: Vreede, F, Jung, T, Brownlee, G
Formato: Journal article
Idioma:English
Publicado em: 2004