Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli

Nucleotide excision repair (NER) removes chemically diverse DNA lesions in all domains of life. In Escherichia coli, UvrA and UvrB initiate NER, although the mechanistic details of how this occurs in vivo remain to be established. Here we provide, using single-molecule fluorescence imaging, a compre...

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Bibliographic Details
Main Authors: Stracy, M, Jaciuk, M, Uphoff, S, Kapanidis, A, Nowotny, M, Sherratt, D, Zawadzki, P
Format: Journal article
Published: Nature Publishing Group 2016