Preliminary studies on the transformation of nitrosugars into branched chain iminosugars: synthesis of 1,4-dideoxy-4-C-hydroxymethyl-1,4-imino-pentanols.

A novel promising strategy for the transformation of nitrosugars into branched pyrrolidines, based on double Henry reaction with formaldehyde followed by reductive ring closure, allowed the first enantiospecific synthesis of a 4-C-hydroxymethyl branched derivative of the well-known glycosidase inhib...

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Hlavní autoři: Otero, J, Soengas, R, Estévez, J, Estévez, R, Watkin, D, Evinson, E, Nash, R, Fleet, G
Médium: Journal article
Jazyk:English
Vydáno: 2007