Sex hormones and pain: the evidence from functional imaging

There is a substantial body of epidemiological and clinical evidence suggesting that the sex hormones, particularly estradiol and progesterone, play a role in pain. Behavioral studies have not been useful in understanding the relationship between sex hormones and pain perception, and certainly have...

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Main Authors: Vincent, K, Tracey, I
Format: Journal article
Language:English
Published: Springer 2010
Subjects:
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author Vincent, K
Tracey, I
author_facet Vincent, K
Tracey, I
author_sort Vincent, K
collection OXFORD
description There is a substantial body of epidemiological and clinical evidence suggesting that the sex hormones, particularly estradiol and progesterone, play a role in pain. Behavioral studies have not been useful in understanding the relationship between sex hormones and pain perception, and certainly have not helped to elucidate the mechanisms by which such effects may be mediated. This review aims to address the additional insights functional imaging has given us into the role of sex hormones in pain. Functional imaging techniques and experimental designs are discussed before the literature investigating specific questions relating to hormones and pain is reviewed. Finally, we conclude by considering how results of studies imaging the influence of sex hormones in related areas such as emotion and cognition also may inform our understanding of this complex area.
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spelling oxford-uuid:8e1f920b-abf6-4b9c-9020-c53810f39b172022-03-26T22:55:33ZSex hormones and pain: the evidence from functional imagingJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:8e1f920b-abf6-4b9c-9020-c53810f39b17AnaestheticsNeuroscienceEnglishOxford University Research Archive - ValetSpringer2010Vincent, KTracey, IThere is a substantial body of epidemiological and clinical evidence suggesting that the sex hormones, particularly estradiol and progesterone, play a role in pain. Behavioral studies have not been useful in understanding the relationship between sex hormones and pain perception, and certainly have not helped to elucidate the mechanisms by which such effects may be mediated. This review aims to address the additional insights functional imaging has given us into the role of sex hormones in pain. Functional imaging techniques and experimental designs are discussed before the literature investigating specific questions relating to hormones and pain is reviewed. Finally, we conclude by considering how results of studies imaging the influence of sex hormones in related areas such as emotion and cognition also may inform our understanding of this complex area.
spellingShingle Anaesthetics
Neuroscience
Vincent, K
Tracey, I
Sex hormones and pain: the evidence from functional imaging
title Sex hormones and pain: the evidence from functional imaging
title_full Sex hormones and pain: the evidence from functional imaging
title_fullStr Sex hormones and pain: the evidence from functional imaging
title_full_unstemmed Sex hormones and pain: the evidence from functional imaging
title_short Sex hormones and pain: the evidence from functional imaging
title_sort sex hormones and pain the evidence from functional imaging
topic Anaesthetics
Neuroscience
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AT traceyi sexhormonesandpaintheevidencefromfunctionalimaging