Further observations on LKB1/STK11 status and cancer risk in Peutz-Jeghers syndrome.

Further observations on LKB1/STK11 status and cancer risk in Peutz-Jeghers syndrome.

Germline mutations in the LKB1/STK11 tumour suppressor gene cause Peutz-Jeghers syndrome (PJS), a rare dominant disorder. In addition to typical hamartomatous gastrointestinal polyps and pigmented perioral lesions, PJS is associated with an increased risk of tumours at multiple sites. Follow-up info...

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Bibliographic Details
Main Authors:	Lim, W, Hearle, N, Shah, B, Murday, V, Hodgson, S, Lucassen, A, Eccles, D, Talbot, I, Neale, K, Lim, A, O'Donohue, J, Donaldson, A, Macdonald, R, Young, I, Robinson, M, Lee, P, Stoodley, B, Tomlinson, I, Alderson, D, Holbrook, A, Vyas, S, Swarbrick, E, Lewis, A, Phillips, R, Houlston, R
Format:	Journal article
Language:	English
Published:	2003

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