A chemical biology toolbox to study protein methyltransferases and epigenetic signaling

Protein methyltransferases (PMTs) comprise a major class of epigenetic regulatory enzymes with therapeutic relevance. Here we present a collection of chemical probes and associated reagents and data to elucidate the function of human and murine PMTs in cellular studies. Our collection provides inhib...

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Bibliographic Details
Main Authors: Scheer, S, Ackloo, S, Medina, T, Schapira, M, Li, F, Ward, J, Lewis, A, Northrop, J, Richardson, P, Kaniskan, H, Shen, Y, Liu, J, Smil, D, McLeod, D, Zepeda-Velazquez, C, Luo, M, Jin, J, Barsyte-Lovejoy, D, Huber, K, De Carvalho, D, Vedadi, M, Zaph, C, Brown, P, Arrowsmith, C
Format: Journal article
Language:English
Published: Springer Nature 2019