Transcriptional modulation of human endogenous retroviruses in primary CD4+ T xells following vorinostat treatment
The greatest obstacle to a cure for HIV is the provirus that integrates into the genome of the infected cell and persists despite antiretroviral therapy. A “shock and kill” approach has been proposed as a strategy for an HIV cure whereby drugs and compounds referred to as latency-reversing agents (L...
Հիմնական հեղինակներ: | White, C, Beliakova-Bethell, N, Lada, S, Breen, M, Hurst, T, Spina, C, Richman, D, Frater, J, Magiorkinis, G, Woelk, C |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
Frontiers Research Foundation
2018
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