Delaying bacillus Calmette-Guerin vaccination from birth to 4 1/2 months of age reduces postvaccination Th1 and IL-17 responses but leads to comparable mycobacterial responses at 9 months of age.

Bacillus Camette-Guérin (BCG) vaccine is the only licensed vaccine against tuberculosis, yet its protective efficacy is highly variable between different geographical regions. We hypothesized that exposure to nontuberculous mycobacteria attenuates BCG immunogenicity by inducing mycobacterial-specifi...

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書誌詳細
主要な著者: Burl, S, Adetifa, U, Cox, M, Touray, E, Ota, M, Marchant, A, Whittle, H, Mcshane, H, Rowland-Jones, S, Flanagan, K
フォーマット: Journal article
言語:English
出版事項: 2010