Manipulation of indoleamine 2,3-dioxygenase (IDO) for clinical transplantation: promises and challenges

Background: Since the discovery that indoleamine 2,3-dioxygenase (IDO) is a modulator for maintenance of fetomaternal immuno-privilege state, it has been implicated in tumour tolerance, autoimmune diseases and asthma. IDO is an IFN-γ-inducible, intracellular enzyme that catalyzes the initial and rat...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Quan, J, Tan, P, MacDonald, A, Friend, P
Format: Journal article
Język:English
Wydane: 2008