Acyclic quaternary centers from asymmetric conjugate addition of alkylzirconium reagents to linear trisubstituted enones
Synthetic methods for the selective formation of all carbon quaternary centres in non-cyclic systems are rare. Here we report highly enantioselective Cu-catalytic asymmetric conjugate addition of alkylzirconium species to twelve different acyclic trisubstituted enones. A variety of sp(3)-hybridized...
| Автори: | , |
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| Формат: | Journal article |
| Мова: | English |
| Опубліковано: |
Royal Society of Chemistry
2016
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