Molecular networks implicated in speech-related disorders: FOXP2 regulates the SRPX2/uPAR complex.
It is a challenge to identify the molecular networks contributing to the neural basis of human speech. Mutations in transcription factor FOXP2 cause difficulties mastering fluent speech (developmental verbal dyspraxia, DVD), whereas mutations of sushi-repeat protein SRPX2 lead to epilepsy of the rol...
Main Authors: | Roll, P, Vernes, S, Bruneau, N, Cillario, J, Ponsole-Lenfant, M, Massacrier, A, Rudolf, G, Khalife, M, Hirsch, E, Fisher, S, Szepetowski, P |
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Format: | Journal article |
Language: | English |
Published: |
2010
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