The structure of a glycogen phosphorylase glucopyranose spirohydantoin complex at 1.8 A resolution and 100 K: the role of the water structure and its contribution to binding.
A glucopyranose spirohydantoin (a pyranose analogue of the potent herbicide, hydantocidin) has been identified as the highest affinity glucose analogue inhibitor of glycogen phosphorylase b (GPb). In order to elucidate the structural features that contribute to the binding, the structures of GPb in...
المؤلفون الرئيسيون: | Gregoriou, M, Noble, M, Watson, K, Garman, E, Krulle, T, de la Fuente, C, Fleet, G, Oikonomakos, N, Johnson, L |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
1998
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مواد مشابهة
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Glucopyranose spirohydantoins: Specific inhibitors of glycogen phosphorylase
حسب: delaFuente, C, وآخرون
منشور في: (1997) -
Stereospecific synthesis of spirohydantoins of beta-glucopyranose: Inhibitors of glycogen phosphorylase
حسب: Krulle, T, وآخرون
منشور في: (1997) -
Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
حسب: Watson, K, وآخرون
منشور في: (2005) -
POTENT INHIBITION OF GLYCOGEN-PHOSPHORYLASE BY A SPIROHYDANTOIN OF GLUCOPYRANOSE - FIRST PYRANOSE ANALOGS OF HYDANTOCIDIN
حسب: Bichard, C, وآخرون
منشور في: (1995) -
SPECIFIC-INHIBITION OF GLYCOGEN-PHOSPHORYLASE BY A SPIRODIKETOPIPERAZINE AT THE ANOMERIC POSITION OF GLUCOPYRANOSE
حسب: Krulle, T, وآخرون
منشور في: (1995)