The structure of a glycogen phosphorylase glucopyranose spirohydantoin complex at 1.8 A resolution and 100 K: the role of the water structure and its contribution to binding.

The structure of a glycogen phosphorylase glucopyranose spirohydantoin complex at 1.8 A resolution and 100 K: the role of the water structure and its contribution to binding.

A glucopyranose spirohydantoin (a pyranose analogue of the potent herbicide, hydantocidin) has been identified as the highest affinity glucose analogue inhibitor of glycogen phosphorylase b (GPb). In order to elucidate the structural features that contribute to the binding, the structures of GPb in...

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Bibliografiske detaljer
Main Authors:	Gregoriou, M, Noble, M, Watson, K, Garman, E, Krulle, T, de la Fuente, C, Fleet, G, Oikonomakos, N, Johnson, L
Format:	Journal article
Sprog:	English
Udgivet:	1998

Lignende værker

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