2,5-Disubstituted pyrrolidines: versatile regioselective and diastereoselective synthesis by enamine reduction and subsequent alkylation.
A direct and versatile route enabling the regio- and diastereoselective synthesis of 2,5-disubstituted pyrrolidines by reduction of enamines derived from pyroglutamic acid is reported.
Main Authors: | Hussaini, SR, Moloney, M |
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Format: | Journal article |
Language: | English |
Published: |
2003
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