A comprehensive proteomics and genomics analysis reveals novel transmembrane proteins in human platelets and mouse megakaryocytes including G6b-B, a novel immunoreceptor tyrosine-based inhibitory motif protein.

A comprehensive proteomics and genomics analysis reveals novel transmembrane proteins in human platelets and mouse megakaryocytes including G6b-B, a novel immunoreceptor tyrosine-based inhibitory motif protein.

The platelet surface is poorly characterized due to the low abundance of many membrane proteins and the lack of specialist tools for their investigation. In this study we identified novel human platelet and mouse megakaryocyte membrane proteins using specialist proteomics and genomics approaches. Th...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Senis, Y, Tomlinson, M, García, A, Dumon, S, Heath, V, Herbert, J, Cobbold, S, Spalton, J, Ayman, S, Antrobus, R, Zitzmann, N, Bicknell, R, Frampton, J, Authi, K, Martin, A, Wakelam, M, Watson, S
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	American Society for Biochemistry and Molecular Biology 2007

Eitemau Tebyg

A global proteomics approach identifies novel phosphorylated signaling proteins in GPVI-activated platelets: involvement of G6f, a novel platelet Grb2-binding membrane adapter.
gan: García, A, et al.
Cyhoeddwyd: (2006)

Transmembrane Complexes of DAP12 Crystallized in Lipid Membranes Provide Insights into Control of Oligomerization in Immunoreceptor Assembly
gan: Konstantin Knoblich, et al.
Cyhoeddwyd: (2015-05-01)

Lipid-protein interactions of immunoreceptor signaling subunit cytoplasmic domains
gan: Aivazian, Dikran A. (Dikran Arvid), 1971-
Cyhoeddwyd: (2005)

Ligand requirements for immunoreceptor triggering
gan: Barton, MI, et al.
Cyhoeddwyd: (2024)

Immunorecognition and immunoreceptors in the Cnidaria
gan: SR Dunn
Cyhoeddwyd: (2009-02-01)

Aberrant trafficking of transmembrane proteins in human disease.
gan: Cobbold, C, et al.
Cyhoeddwyd: (2003)

Impaired Fracture Healing Caused by Deficiency of the Immunoreceptor Adaptor Protein DAP12.
gan: Masayuki Kamimura, et al.
Cyhoeddwyd: (2015-01-01)

Probing the Immunoreceptor Tyrosine-Based Inhibition Motif Interaction Protein Partners with Proteomics
gan: Yujun Gao, et al.
Cyhoeddwyd: (2024-04-01)

Structure of the transmembrane domain of Salmonella insertion protein B (SipB). Mechanism of insertion investigated by novel biophysical and computational methodologies.
gan: Torres, Jaume.
Cyhoeddwyd: (2008)

Ligand requirements for immunoreceptor triggering
gan: Michael I. Barton, et al.
Cyhoeddwyd: (2024-09-01)

Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B
gan: Timo Vögtle, et al.
Cyhoeddwyd: (2019-08-01)

Discovering immunoreceptor coupling and organization motifs
gan: Michael Reth, et al.
Cyhoeddwyd: (2023-09-01)

A Novel Type III Endosome Transmembrane Protein, TEMP
gan: Rohan D. Teasdale, et al.
Cyhoeddwyd: (2012-11-01)

The bHLH protein SCL/Tal-l interacts with the co-repressor ETO-2 in erythroid cells and megakaryocytes.
gan: Schuh, A, et al.
Cyhoeddwyd: (2005)

A novel family of mammalian transmembrane proteins involved in cholesterol transport
gan: Kevin M. Méndez-Acevedo, et al.
Cyhoeddwyd: (2017-08-01)

Genetic interactions between UNC-17/VAChT and a novel transmembrane protein in Caenorhabditis elegans.
gan: Mathews, E, et al.
Cyhoeddwyd: (2012)

Roles for the FCRL6 Immunoreceptor in Tumor Immunology
gan: Randall S. Davis
Cyhoeddwyd: (2020-10-01)

Transmembrane protein 208: a novel ER-localized protein that regulates autophagy and ER stress.
gan: Yuanbo Zhao, et al.
Cyhoeddwyd: (2013-01-01)

The Transmembrane Conformation of the Influenza B Virus M2 Protein in Lipid Bilayers
gan: Mandala, Venkata S, et al.
Cyhoeddwyd: (2021)

The Transmembrane Conformation of the Influenza B Virus M2 Protein in Lipid Bilayers
gan: Mandala, Venkata S, et al.
Cyhoeddwyd: (2022)

Protein 2B of Coxsackievirus B3 Induces Autophagy Relying on Its Transmembrane Hydrophobic Sequences
gan: Heng Wu, et al.
Cyhoeddwyd: (2016-05-01)

Characterization of megakaryocyte GATA1-interacting proteins: the corepressor ETO2 and GATA1 interact to regulate terminal megakaryocyte maturation.
gan: Hamlett, I, et al.
Cyhoeddwyd: (2008)

Transmembrane signal transduction by peptide hormones via family B G protein-coupled receptors
gan: Kelly J Culhane, et al.
Cyhoeddwyd: (2015-11-01)

Identification and characterization of a novel tyrosine kinase from megakaryocytes
gan: Bennett, B, et al.
Cyhoeddwyd: (1994)

RIEDL tag: A novel pentapeptide tagging system for transmembrane protein purification
gan: Teizo Asano, et al.
Cyhoeddwyd: (2020-09-01)

Influence of medication “Membranostabil” on expression of immunoreceptor proteins in small intestine of ruminants during the period of formation of colostral immunity
gan: S. I. Holopura, et al.
Cyhoeddwyd: (2019-12-01)

IDENTIFICATION AND CHARACTERIZATION OF A NOVEL TYROSINE KINASE FROM MEGAKARYOCYTES
gan: Avraham, H, et al.
Cyhoeddwyd: (1993)

Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti
gan: Yoann Saucereau, et al.
Cyhoeddwyd: (2022-08-01)

Transmembrane protein 184B (TMEM184B) promotes expression of synaptic gene networks in the mouse hippocampus
gan: Elizabeth B. Wright, et al.
Cyhoeddwyd: (2023-09-01)

Proteomic analysis of HepaRG cells: a novel cell line that supports hepatitis B virus infection.
gan: Narayan, R, et al.
Cyhoeddwyd: (2009)

Amantadine blocks channel activity of the transmembrane segment of the NB protein from influenza B.
gan: Fischer, W, et al.
Cyhoeddwyd: (2001)

Role of S protein transmembrane domain mutations in the development of occult hepatitis B virus infection
gan: Xinyi Jiang, et al.
Cyhoeddwyd: (2022-12-01)

TMEM120A and B: Nuclear Envelope Transmembrane Proteins Important for Adipocyte Differentiation.
gan: Dzmitry G Batrakou, et al.
Cyhoeddwyd: (2015-01-01)

Megakaryocyte lineage development is controlled by modulation of protein acetylation.
gan: Marije Bartels, et al.
Cyhoeddwyd: (2018-01-01)

Expression and regulation of transcript for the novel transmembrane protein Tmem182 in the adipocyte and muscle lineage
gan: Smas Cynthia M, et al.
Cyhoeddwyd: (2008-09-01)

Transmembrane and coiled-coil domain family 1 is a novel protein of the endoplasmic reticulum.
gan: Chao Zhang, et al.
Cyhoeddwyd: (2014-01-01)

Analysis and prediction of interactions between transmembrane and non-transmembrane proteins
gan: Chang Lu, et al.
Cyhoeddwyd: (2024-04-01)

Novel Heparin Receptor Transmembrane Protein 184a Regulates Angiogenesis in the Adult Zebrafish Caudal Fin
gan: Sara Lynn N. Farwell, et al.
Cyhoeddwyd: (2017-09-01)

Erratum to: Immunorecognition and immunoreceptors in the Cnidaria [6: 7-14, 2009]
gan: S R Dunn
Cyhoeddwyd: (2009-02-01)

Immunorecognition and immunoreceptors in the Cnidaria [For this article an Erratum has been published]
gan: S R Dunn
Cyhoeddwyd: (2009-01-01)