Survival probability of drug resistant mutants in malaria parasites.

Survival probability of drug resistant mutants in malaria parasites.

This study predicts the ultimate probability of survival of a newly arisen drug resistant mutant in a population of malaria parasites, with a view to understanding what conditions favour the evolution of drug resistance. Using branching process theory and a population genetics transmission model, th...

Full description

Bibliographic Details
Main Author:	Mackinnon, M
Format:	Journal article
Language:	English
Published:	1997

Similar Items

Survival probability of drug resistant mutants in malaria parasites (vol 264, pg 53, 1997)
by: Mackinnon, M
Published: (1997)

The evolution of multiple drug resistance in malaria parasites.
by: Mackinnon, M, et al.
Published: (1998)

Drug resistance models for malaria.
by: Mackinnon, M
Published: (2005)

The emergence of drug-resistant malaria.
by: Hastings, I, et al.
Published: (1998)

Evolution of drug resistance in malaria parasites
by: Legros Mathieu, et al.
Published: (2012-10-01)

The selection landscape of malaria parasites.
by: Mackinnon, M, et al.
Published: (2010)

A chloroquine resistance locus in the rodent malaria parasite Plasmodium chabaudi.
by: Carlton, J, et al.
Published: (1998)

The apicoplast link to fever-survival and artemisinin-resistance in the malaria parasite
by: Min Zhang, et al.
Published: (2021-07-01)

The de novo selection of drug-resistant malaria parasites.
by: White, N, et al.
Published: (2003)

Drug resistance in malaria: its population biology and implications for control.
by: Babiker, H, et al.
Published: (2005)

Culture adaptation of malaria parasites selects for convergent loss-of-function mutants
by: Kwiatkowski, D, et al.
Published: (2017)

Selection for high and low virulence in the malaria parasite Plasmodium chabaudi.
by: Mackinnon, M, et al.
Published: (1999)

GAPDH mediates drug resistance and metabolism in Plasmodium falciparum malaria parasites.
by: Andrew J Jezewski, et al.
Published: (2022-09-01)

Cytoprotective autophagy as a pro-survival strategy in ART-resistant malaria parasites
by: Deepika Kannan, et al.
Published: (2023-05-01)

Drug resistance. Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance.
by: Mok, S, et al.
Published: (2015)

Transcriptional variation in human malaria parasites and its association with drug resistance
by: Mok, Sachel
Published: (2013)

Drug-Resistant Malaria Parasites Introduced into Madagascar from Comoros Islands
by: Didier Ménard, et al.
Published: (2007-11-01)

Mosquito transmission, growth phenotypes and the virulence of malaria parasites.
by: Pollitt, L, et al.
Published: (2013)

Virulence in rodent malaria: host genotype by parasite genotype interactions.
by: Mackinnon, M, et al.
Published: (2002)

Enhanced transmission of drug-resistant parasites to mosquitoes following drug treatment in rodent malaria.
by: Andrew S Bell, et al.
Published: (2012-01-01)

Antimalarial drugs clear resistant parasites from partially immune hosts.
by: Cravo, P, et al.
Published: (2001)

Propensity of selecting mutant parasites for the antimalarial drug cabamiquine
by: Eva Stadler, et al.
Published: (2023-08-01)

Genetic relationships between parasite virulence and transmission in the rodent malaria Plasmodium chabaudi
by: Mackinnon, M, et al.
Published: (1999)

Molecular Mechanisms for Drug Hypersensitivity Induced by the Malaria Parasite's Chloroquine Resistance Transporter.
by: Sashika N Richards, et al.
Published: (2016-07-01)

Nanopore sequencing of drug-resistance-associated genes in malaria parasites, Plasmodium falciparum
by: Runtuwene, LR, et al.
Published: (2018)

Transmission of artemisinin-resistant malaria parasites to mosquitoes under antimalarial drug pressure
by: Witmer, K, et al.
Published: (2020)

The effects of host immunity on virulence-transmissibility relationships in the rodent malaria parasite Plasmodium chabaudi.
by: Mackinnon, M, et al.
Published: (2003)

In artemisinin-resistant falciparum malaria parasites, mitochondrial metabolic pathways are essential for survival but not those of apicoplast
by: Manel Ouji, et al.
Published: (2024-12-01)

Repurposing Drugs to Fight Hepatic Malaria Parasites
by: Diana Fontinha, et al.
Published: (2020-07-01)

Heterochromatin Protein 1 Secures Survival and Transmission of Malaria Parasites
by: Brancucci, Nicolas M.B., et al.
Published: (2016)

Immune selection suppresses the emergence of drug resistance in malaria parasites but facilitates its spread.
by: Alexander O B Whitlock, et al.
Published: (2021-07-01)

Stepwise acquisition of pyrimethamine resistance in the malaria parasite.
by: Lozovsky, E, et al.
Published: (2009)

Author Correction: Propensity of selecting mutant parasites for the antimalarial drug cabamiquine
by: Eva Stadler, et al.
Published: (2023-09-01)

Does the drug sensitivity of malaria parasites depend on their virulence?
by: Chan Brian HK, et al.
Published: (2008-12-01)

A stochastic model of antibiotic misuse, economy, and drug resistance: relating mutant extinction probability to socioeconomic and epidemiological factors
by: Bhawna Malik, et al.
Published: (2023-12-01)

Assessing fitness costs in malaria parasites: a comprehensive review and implications for drug resistance management
by: Xyonane Segovia, et al.
Published: (2025-03-01)

Putative molecular markers of Plasmodium falciparum resistance to antimalarial drugs in malaria parasites from Ghana
by: Sena Adzoa Matrevi, et al.
Published: (2024-02-01)

Drug resistance profile and clonality of Plasmodium falciparum parasites in Cape Verde: the 2017 malaria outbreak
by: Silvania Da Veiga Leal, et al.
Published: (2021-03-01)

A Mathematical Analysis of Competitive Dynamics and Aggressive Treatment in the Evolution of Drug Resistance in Malaria Parasites
by: Tianqi Song, et al.
Published: (2024-05-01)

Probability of Transmission of Malaria from Mosquito to Human Is Regulated by Mosquito Parasite Density in Naïve and Vaccinated Hosts.
by: Thomas S Churcher, et al.
Published: (2017-01-01)