Acute and chronic pituitary failure resembling Sheehan's syndrome following bites by Russell's viper in Burma.
Pituitary function was investigated in 9 patients in shock after Russell's viper bites and in 24 individuals who had been severely envenomed 2 weeks to 24 years previously. 3 out of 9 patients had hypoglycaemia and inappropriately low serum cortisol, plasma growth hormone, and plasma prolactin...
| Huvudupphovsmän: | , , , , , , |
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| Materialtyp: | Journal article |
| Språk: | English |
| Publicerad: |
1987
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| _version_ | 1826284642482782208 |
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| author | Tun-Pe Phillips, R Warrell, D Moore, R Tin-Nu-Swe Myint-Lwin Burke, C |
| author_facet | Tun-Pe Phillips, R Warrell, D Moore, R Tin-Nu-Swe Myint-Lwin Burke, C |
| author_sort | Tun-Pe |
| collection | OXFORD |
| description | Pituitary function was investigated in 9 patients in shock after Russell's viper bites and in 24 individuals who had been severely envenomed 2 weeks to 24 years previously. 3 out of 9 patients had hypoglycaemia and inappropriately low serum cortisol, plasma growth hormone, and plasma prolactin concentrations. 4 who died had pituitary haemorrhage and 1 had adrenal haemorrhage as well. Of the 24 who had apparently recovered from bites, 7 had clinical features of hypopituitarism and no response in plasma growth hormone or prolactin concentrations to symptom-producing insulin-induced hypoglycaemia. 4 of these 7 had a sluggish serum cortisol response to 'Synacthen Depot' and 5 had an abnormal cortisol response to hypoglycaemia. 4 men with symptoms who were tested had low serum testosterone concentrations; serum thyroxine was also low in these men but not in 2 women with menstrual disturbances and impaired insulin responses. Of the 17 individuals without clinical evidence of endocrine disease, 4 had pituitary hormonal abnormalities. Russell's viper envenoming may thus produce a disorder resembling Sheehan's syndrome. |
| first_indexed | 2024-03-07T01:16:55Z |
| format | Journal article |
| id | oxford-uuid:8eff7c4a-7971-42a1-b01f-c6a1631550f1 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T01:16:55Z |
| publishDate | 1987 |
| record_format | dspace |
| spelling | oxford-uuid:8eff7c4a-7971-42a1-b01f-c6a1631550f12022-03-26T23:01:20ZAcute and chronic pituitary failure resembling Sheehan's syndrome following bites by Russell's viper in Burma.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:8eff7c4a-7971-42a1-b01f-c6a1631550f1EnglishSymplectic Elements at Oxford1987Tun-PePhillips, RWarrell, DMoore, RTin-Nu-SweMyint-LwinBurke, CPituitary function was investigated in 9 patients in shock after Russell's viper bites and in 24 individuals who had been severely envenomed 2 weeks to 24 years previously. 3 out of 9 patients had hypoglycaemia and inappropriately low serum cortisol, plasma growth hormone, and plasma prolactin concentrations. 4 who died had pituitary haemorrhage and 1 had adrenal haemorrhage as well. Of the 24 who had apparently recovered from bites, 7 had clinical features of hypopituitarism and no response in plasma growth hormone or prolactin concentrations to symptom-producing insulin-induced hypoglycaemia. 4 of these 7 had a sluggish serum cortisol response to 'Synacthen Depot' and 5 had an abnormal cortisol response to hypoglycaemia. 4 men with symptoms who were tested had low serum testosterone concentrations; serum thyroxine was also low in these men but not in 2 women with menstrual disturbances and impaired insulin responses. Of the 17 individuals without clinical evidence of endocrine disease, 4 had pituitary hormonal abnormalities. Russell's viper envenoming may thus produce a disorder resembling Sheehan's syndrome. |
| spellingShingle | Tun-Pe Phillips, R Warrell, D Moore, R Tin-Nu-Swe Myint-Lwin Burke, C Acute and chronic pituitary failure resembling Sheehan's syndrome following bites by Russell's viper in Burma. |
| title | Acute and chronic pituitary failure resembling Sheehan's syndrome following bites by Russell's viper in Burma. |
| title_full | Acute and chronic pituitary failure resembling Sheehan's syndrome following bites by Russell's viper in Burma. |
| title_fullStr | Acute and chronic pituitary failure resembling Sheehan's syndrome following bites by Russell's viper in Burma. |
| title_full_unstemmed | Acute and chronic pituitary failure resembling Sheehan's syndrome following bites by Russell's viper in Burma. |
| title_short | Acute and chronic pituitary failure resembling Sheehan's syndrome following bites by Russell's viper in Burma. |
| title_sort | acute and chronic pituitary failure resembling sheehan s syndrome following bites by russell s viper in burma |
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