Requirement for Lyl1 in a model of Lmo2-driven early T-cell precursor ALL.

Requirement for Lyl1 in a model of Lmo2-driven early T-cell precursor ALL.

Lmo2 is an oncogenic transcription factor that is frequently overexpressed in T-cell acute lymphoblastic leukemia (T-ALL), including early T-cell precursor ALL (ETP-ALL) cases with poor prognosis. Lmo2 must be recruited to DNA by binding to the hematopoietic basic helix-loop-helix factors Scl/Tal1 o...

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Dades bibliogràfiques
Autors principals:	McCormack, M, Shields, B, Jackson, J, Nasa, C, Shi, W, Slater, N, Tremblay, C, Rabbitts, T, Curtis, D
Format:	Journal article
Idioma:	English
Publicat:	2013

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