Reprogramming T cells: the role of extracellular matrix in coordination of T cell activation and migration.
The stable immunological synapse between a T cell and antigen-presenting cell coordinates migration and activation. Three-dimensional collagen gels transform this interaction into a series of transient hit-and-run encounters. Here we integrate these alternative modes of interaction in a model for pr...
| Main Authors: | , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
2001
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| 总结: | The stable immunological synapse between a T cell and antigen-presenting cell coordinates migration and activation. Three-dimensional collagen gels transform this interaction into a series of transient hit-and-run encounters. Here we integrate these alternative modes of interaction in a model for primary T cell activation and effector function in vivo. |
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