Reprogramming T cells: the role of extracellular matrix in coordination of T cell activation and migration.

The stable immunological synapse between a T cell and antigen-presenting cell coordinates migration and activation. Three-dimensional collagen gels transform this interaction into a series of transient hit-and-run encounters. Here we integrate these alternative modes of interaction in a model for pr...

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Main Authors: Dustin, M, de Fougerolles, A
Format: Journal article
Language:English
Published: 2001
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author Dustin, M
de Fougerolles, A
author_facet Dustin, M
de Fougerolles, A
author_sort Dustin, M
collection OXFORD
description The stable immunological synapse between a T cell and antigen-presenting cell coordinates migration and activation. Three-dimensional collagen gels transform this interaction into a series of transient hit-and-run encounters. Here we integrate these alternative modes of interaction in a model for primary T cell activation and effector function in vivo.
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spelling oxford-uuid:8f21d3be-d0f8-4bb4-b7a4-85d947c3acb92022-03-26T23:02:20ZReprogramming T cells: the role of extracellular matrix in coordination of T cell activation and migration.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:8f21d3be-d0f8-4bb4-b7a4-85d947c3acb9EnglishSymplectic Elements at Oxford2001Dustin, Mde Fougerolles, AThe stable immunological synapse between a T cell and antigen-presenting cell coordinates migration and activation. Three-dimensional collagen gels transform this interaction into a series of transient hit-and-run encounters. Here we integrate these alternative modes of interaction in a model for primary T cell activation and effector function in vivo.
spellingShingle Dustin, M
de Fougerolles, A
Reprogramming T cells: the role of extracellular matrix in coordination of T cell activation and migration.
title Reprogramming T cells: the role of extracellular matrix in coordination of T cell activation and migration.
title_full Reprogramming T cells: the role of extracellular matrix in coordination of T cell activation and migration.
title_fullStr Reprogramming T cells: the role of extracellular matrix in coordination of T cell activation and migration.
title_full_unstemmed Reprogramming T cells: the role of extracellular matrix in coordination of T cell activation and migration.
title_short Reprogramming T cells: the role of extracellular matrix in coordination of T cell activation and migration.
title_sort reprogramming t cells the role of extracellular matrix in coordination of t cell activation and migration
work_keys_str_mv AT dustinm reprogrammingtcellstheroleofextracellularmatrixincoordinationoftcellactivationandmigration
AT defougerollesa reprogrammingtcellstheroleofextracellularmatrixincoordinationoftcellactivationandmigration