Immobilization of engineered arginase on gold-carbon nanotubes.
It is demonstrated that engineered arginase with a single protruded site of cysteine deliberately placed away from its active centre by site-directed mutagenesis can facilitate its attachment on a gold-nanoparticle surface with atomic precision, resulting in no apparent loss in enzymatic activity.
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2012
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| _version_ | 1797081697239433216 |
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| author | Lee, G Kwok, S Yu, C Tam, K Chong, H Leung, Y Tsang, S |
| author_facet | Lee, G Kwok, S Yu, C Tam, K Chong, H Leung, Y Tsang, S |
| author_sort | Lee, G |
| collection | OXFORD |
| description | It is demonstrated that engineered arginase with a single protruded site of cysteine deliberately placed away from its active centre by site-directed mutagenesis can facilitate its attachment on a gold-nanoparticle surface with atomic precision, resulting in no apparent loss in enzymatic activity. |
| first_indexed | 2024-03-07T01:17:36Z |
| format | Journal article |
| id | oxford-uuid:8f3bec27-77e6-4c8f-91c3-7e539feac618 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T01:17:36Z |
| publishDate | 2012 |
| record_format | dspace |
| spelling | oxford-uuid:8f3bec27-77e6-4c8f-91c3-7e539feac6182022-03-26T23:02:56ZImmobilization of engineered arginase on gold-carbon nanotubes.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:8f3bec27-77e6-4c8f-91c3-7e539feac618EnglishSymplectic Elements at Oxford2012Lee, GKwok, SYu, CTam, KChong, HLeung, YTsang, SIt is demonstrated that engineered arginase with a single protruded site of cysteine deliberately placed away from its active centre by site-directed mutagenesis can facilitate its attachment on a gold-nanoparticle surface with atomic precision, resulting in no apparent loss in enzymatic activity. |
| spellingShingle | Lee, G Kwok, S Yu, C Tam, K Chong, H Leung, Y Tsang, S Immobilization of engineered arginase on gold-carbon nanotubes. |
| title | Immobilization of engineered arginase on gold-carbon nanotubes. |
| title_full | Immobilization of engineered arginase on gold-carbon nanotubes. |
| title_fullStr | Immobilization of engineered arginase on gold-carbon nanotubes. |
| title_full_unstemmed | Immobilization of engineered arginase on gold-carbon nanotubes. |
| title_short | Immobilization of engineered arginase on gold-carbon nanotubes. |
| title_sort | immobilization of engineered arginase on gold carbon nanotubes |
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