Genetic and functional data identifying Cd101 as a type 1 diabetes (T1D) susceptibility gene in nonobese diabetic (NOD) mice

Type 1 diabetes (T1D) is a chronic multi-factorial disorder characterized by the immune-mediated destruction of insulin-producing pancreatic beta cells. Variations at a large number of genes influence susceptibility to spontaneous autoimmune T1D in non-obese diabetic (NOD) mice, one of the most freq...

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Bibliographic Details
Main Authors: Mattner, J, Mohammed, JP, Fusakio, ME, Giessler, C, Hackstein, C-P, Opoka, R, Wrage, M, Schey, R, Clark, J, Fraser, HI, Rainbow, DB, Wicker, LS
Format: Journal article
Language:English
Published: Public Library of Science 2019