BET inhibition disrupts transcription but retains enhancer-promoter contact

Enhancers are DNA sequences that enable complex temporal and tissue-specific regulation of genes in higher eukaryotes. Although it is not entirely clear how enhancer-promoter interactions can increase gene expression, this proximity has been observed in multiple systems at multiple loci and is thoug...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Nicholas Crump, Erica Ballabio, Laura Godfrey, Ross Thorne, Emmanouela Repapi, Jon Kerry, Marta Tapia, Peng Hua, Panagis Filippakopoulos, James Davies, Thomas Milne
Format: Journal article
Język:English
Wydane: Springer Nature 2019