Generation of a novel endogenously StrepII/FLAG tagged system for the identification of the vertebrate FANCJ associated proteins
Fanconi Anaemia (FA) is a rare inherited chromosomal instability disorder characterized by developmental abnormalities, bone marrow failure, increased risk of developing cancer and an increased cellular sensitivity to DNA interstrand crosslinking compounds, including the anticancer drugs, cisplatin,...
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| Médium: | Diplomová práce |
| Jazyk: | English |
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2012
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