Photochemical alkene isomerization for the synthesis of polysubstituted furans and pyrroles under neutral conditions
A photochemical approach to polysubstituted heterocycles using UV‐induced alkene isomerization is described. The method allows for the synthesis of disubstituted furans and pyrroles under mild and neutral conditions and also provides access to a class of trisubstituted furans pertinent to natural‐pr...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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Wiley
2019
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| _version_ | 1797081737987096576 |
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| author | Walker, J Werrel, S Donohoe, T |
| author_facet | Walker, J Werrel, S Donohoe, T |
| author_sort | Walker, J |
| collection | OXFORD |
| description | A photochemical approach to polysubstituted heterocycles using UV‐induced alkene isomerization is described. The method allows for the synthesis of disubstituted furans and pyrroles under mild and neutral conditions and also provides access to a class of trisubstituted furans pertinent to natural‐product synthesis. The method has broad functional‐group tolerance and many richly decorated heterocycles have been prepared incorporating functional groups that are unstable under Brønsted and Lewis acidic conditions. |
| first_indexed | 2024-03-07T01:18:13Z |
| format | Journal article |
| id | oxford-uuid:8f712a76-e7d8-4a8f-8f05-858c12c54f11 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T01:18:13Z |
| publishDate | 2019 |
| publisher | Wiley |
| record_format | dspace |
| spelling | oxford-uuid:8f712a76-e7d8-4a8f-8f05-858c12c54f112022-03-26T23:04:16ZPhotochemical alkene isomerization for the synthesis of polysubstituted furans and pyrroles under neutral conditionsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:8f712a76-e7d8-4a8f-8f05-858c12c54f11EnglishSymplectic Elements at OxfordWiley2019Walker, JWerrel, SDonohoe, TA photochemical approach to polysubstituted heterocycles using UV‐induced alkene isomerization is described. The method allows for the synthesis of disubstituted furans and pyrroles under mild and neutral conditions and also provides access to a class of trisubstituted furans pertinent to natural‐product synthesis. The method has broad functional‐group tolerance and many richly decorated heterocycles have been prepared incorporating functional groups that are unstable under Brønsted and Lewis acidic conditions. |
| spellingShingle | Walker, J Werrel, S Donohoe, T Photochemical alkene isomerization for the synthesis of polysubstituted furans and pyrroles under neutral conditions |
| title | Photochemical alkene isomerization for the synthesis of polysubstituted furans and pyrroles under neutral conditions |
| title_full | Photochemical alkene isomerization for the synthesis of polysubstituted furans and pyrroles under neutral conditions |
| title_fullStr | Photochemical alkene isomerization for the synthesis of polysubstituted furans and pyrroles under neutral conditions |
| title_full_unstemmed | Photochemical alkene isomerization for the synthesis of polysubstituted furans and pyrroles under neutral conditions |
| title_short | Photochemical alkene isomerization for the synthesis of polysubstituted furans and pyrroles under neutral conditions |
| title_sort | photochemical alkene isomerization for the synthesis of polysubstituted furans and pyrroles under neutral conditions |
| work_keys_str_mv | AT walkerj photochemicalalkeneisomerizationforthesynthesisofpolysubstitutedfuransandpyrrolesunderneutralconditions AT werrels photochemicalalkeneisomerizationforthesynthesisofpolysubstitutedfuransandpyrrolesunderneutralconditions AT donohoet photochemicalalkeneisomerizationforthesynthesisofpolysubstitutedfuransandpyrrolesunderneutralconditions |