Stabilization of chromatin topology safeguards genome integrity

Stabilization of chromatin topology safeguards genome integrity

To safeguard genome integrity in response to DNA double-strand breaks (DSBs), mammalian cells mobilize the neighbouring chromatin to shield DNA ends against excessive resection that could undermine repair fidelity and cause damage to healthy chromosomes1. This form of genome surveillance is orchestr...

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Detalles Bibliográficos
Autores principales: Ochs, F, Karemore, G, Miron, E, Brown, J, Sedlackova, H, Rask, M, Lampe, M, Buckle, V, Schermelleh, L, Lukas, J, Lukas, C
Formato: Journal article
Lenguaje:English
Publicado: 2019

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